Bone Marrow Transplant?
ok, first off, CMS101101 is completely WRONG!!!! you don't need to have a twin to have a 100% match. in fact thats not even how they rate matches. I had a bone marrow transplant when I was 17 (now i am 18), none of my siblings were a match so i got on the donor list, and they found a 12 out of 12 match for me, and I am doing GREAT! Also, When you receive things from another person, your body sees it as foreign, EXCEPT IN BONE MARROW TRANSPLANTS! With the bone marrow transplants, you get something called graft V.S. host disease. that is where the donor marrow tries to take over your own body. that is why your mom is on so many drugs. If she wasn't on drugs, the donor marrow would slowly be destroying your mothers internal organs. I also had increased liver levels, but the doctors said that they always see that in these cases. Also, she might have a touch of GVHD (graft v.s. host disease) . if so, ask the doctors about it, I take prednisone to keep mine under control. But if the doctors say that she is doing well, trust them, they know what they are doing! _hope this helps!!!
Bone marrow transplants?
Full blooded siblings are best chance. Parents or children have about 1/8 of a chance of matching. Beyond the immediate family, it is unlikely anyone related will match. Insurance typically wont pay for anyone to be matched outside the immediate family. Other people can be tested, ofcourse, but it is unlikely they will match and will have to pay for test out of pocket. There is a national registry for bone marrow and cord blood donors. He might be a candidate for a cord blood transplant, or a trial with cord blood transplant (I did cord blood, but mine was a trial... using two units of cord blood rather than just one) When looking for a match, they do dna and HLA tissue typing. The tissue type of the patient and donor need to match. It needs to be a near perfect match if using an adult donor. If using cord blood, it can be less of a match (both of my units were tissue mis-matches.. but that only works with cord blood). To do the tests on the donor, they will take blood as well as a bone marrow biopsy. This is to do the dna and tissue typing and also to make sure the donor has healthy marrow. EDIT: lady below me is correct. A bone marrow biopsy is not including in the initial matching tests, but WILL be done before the person can donate to rule out any bone marrow disease or disorder that hasnt reached circulating blood yet. What's the point in having a transplant if your donor has a disease?
My father will need a bone marrow transplant for his cancer, I am 17, can I be the donor?
Chemotherapy can each so often finally end up inflicting Leukemia that's present day in bone marrow...it sounds like it could have grew to become from one variety of maximum cancers to a various for her which easily happens and its unlucky. i'm very sorry!
What does a bone marrow transplant like?
There are three kinds of bone marrow transplants: Autologous bone marrow transplant. "Auto" means "self." Stem cells are taken from the patient before the patient gets chemotherapy or radiation treatment. When chemotherapy or radiation is done, the patient gets their stem cells back. This is called a "rescue" transplant. It allows the patient to receive high doses of chemotherapy and radiation. Allogeneic bone marrow transplant. "Allo" means "other." Stem cells come from another person, who is called a donor. Donor stem cells come from the donor’s bone marrow or their blood. Most times, a donor must have the same genetic typing as the patient, so that their blood "matches" the patient’s. Special blood tests will tell whether a possible donor is a good match for the patient. A patient’s brothers and sisters have the highest chance of being a good match (25% chance for each full sibling), but sometimes parents and children of the patient and other relatives may be matches. Donors who are not related to the patient may be found through national bone marrow registries. Umbilical cord blood transplant. Stem cells are taken from an umbilical cord right after delivery of an infant. The stem cells are tested, typed, counted, and frozen until they are needed for a transplant. Umbilical cord blood requires less stringent matching because the stems cells are so immature. The patient gets the stem cells through a tube called a central venous catheter. The process is similar to receiving a blood transfusion. The cells go right into the bloodstream and find their own way to the bone marrow. Usually, no surgery is required. Donors may have minor surgery to collect their bone marrow and stem cells. For a bone marrow harvest, they will be unconscious and pain-free (under general anesthesia) while their bone marrow is removed from their hip bone. In many cases however, stem cells can be collected right from the blood. The donor will first receive injections for a few days. When receiving stem cells, a patient may have these symptoms: Pain Chills Fever Hives Chest pain Drop in blood pressure Shortness of breath Nausea Flushing Headache Funny taste in the mouth
What is the process of bone marrow transplant?
There are three kinds of bone marrow transplants: * Autologous bone marrow transplant. "Auto" means "self." Stem cells are taken from the patient before the patient gets chemotherapy or radiation treatment. When chemotherapy or radiation is done, the patient gets their stem cells back. This is called a "rescue" transplant. * Allogeneic bone marrow transplant. "Allo" means "other." Stem cells come from another person, who is called a donor. Donor stem cells come from the donor’s bone marrow or their blood. Most times, a donor must have the same genetic typing as the patient, so that their blood "matches" the patient’s. Special blood tests will tell whether a possible donor is a good match for the patient. A patient’s brothers and sisters have the highest chance of being a good match. But, sometimes parents and children of the patient and other relatives may be matches. Donors who are not related to the patient may be found through national bone marrow registries. These are lists of people who have offered to be donors. * Umbilical cord blood transplant. Stem cells are taken from an umbilical cord right after delivery of an infant. The stem cells are tested, typed, counted, and frozen until they are needed for a transplant.
Question about Bone Marrow transplants....?
CasparPie, There are two types of bone marrow transplants – an Autologous bone marrow transplant, where the donor is the person him/herself and an Allogenic bone marrow transplant where the donor is another person whose tissue has the same genetic type as the person needing the transplant (recipient). If a family member does not match the recipient, the National/International Bone Marrow Donor/Transplant Program Registry database is searched for an unrelated individual whose tissue type is a close match. It is more likely that a donor who comes from the same racial or ethnic group as the recipient will have the same tissue traits. It is highly unlikely that two friends will share the same genetic profile. However in the unlikely event that they are matched, then the wishes of the friend would be taken into consideration and the donation would go ahead between the two friends. It would not be considered as 'jumping the queue.' The best hope for any patient lies with the potential donors who are already listed worldwide. However, as long as your friend is willing to donate to any patient, and meets the program's eligibility requirements – the friend can be tested and be registered with The National/International Bone Marrow Donor/Transplant Register or any similar group or organisation. ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. - MANY ANSWERS ARE FLAWED. It is extremely important to obtain an accurate diagnosis before trying to find a cure. Many diseases and conditions share common symptoms. The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Hope this helps matador 89
What does a bone marrow transplant like?
There are three kinds of bone marrow transplants: Autologous bone marrow transplant. "Auto" means "self." Stem cells are taken from the patient before the patient gets chemotherapy or radiation treatment. When chemotherapy or radiation is done, the patient gets their stem cells back. This is called a "rescue" transplant. It allows the patient to receive high doses of chemotherapy and radiation. Allogeneic bone marrow transplant. "Allo" means "other." Stem cells come from another person, who is called a donor. Donor stem cells come from the donor’s bone marrow or their blood. Most times, a donor must have the same genetic typing as the patient, so that their blood "matches" the patient’s. Special blood tests will tell whether a possible donor is a good match for the patient. A patient’s brothers and sisters have the highest chance of being a good match (25% chance for each full sibling), but sometimes parents and children of the patient and other relatives may be matches. Donors who are not related to the patient may be found through national bone marrow registries. Umbilical cord blood transplant. Stem cells are taken from an umbilical cord right after delivery of an infant. The stem cells are tested, typed, counted, and frozen until they are needed for a transplant. Umbilical cord blood requires less stringent matching because the stems cells are so immature. The patient gets the stem cells through a tube called a central venous catheter. The process is similar to receiving a blood transfusion. The cells go right into the bloodstream and find their own way to the bone marrow. Usually, no surgery is required. Donors may have minor surgery to collect their bone marrow and stem cells. For a bone marrow harvest, they will be unconscious and pain-free (under general anesthesia) while their bone marrow is removed from their hip bone. In many cases however, stem cells can be collected right from the blood. The donor will first receive injections for a few days. When receiving stem cells, a patient may have these symptoms: Pain Chills Fever Hives Chest pain Drop in blood pressure Shortness of breath Nausea Flushing Headache Funny taste in the mouth
What is the best hospital for bone marrow transplants in India?
Looking over the answers so far most of the responses appear to be superficial and cut and pasted from online marketing websites. While it may be useful for families to know the variety of institutions available within India, BMT outcomes and cost are key to deciding whether a patient will receive quality care, and unfortunately these data are still profoundly lacking in the public domain. The knowledge asymmetry in the field of medicine, especially complex procedures such as BMT, is vast, even in a high-income country like USA. There are many dedicated physicians in the private sector in India, but the fact That BMT is driven by corporate profit creates a bias, whether conscious or unconscious.In the absence of a consumer organization sponsored data-driven registry some questions that patients need to ask:Is BMT needed and if it is performed what are the outcomes for that particular disease or condition as a standard of care? Is it urgent e.g. relapsed leukemia, or elective e.g. thalassemia. Remember that BMT units transplant a variety of diagnoses so overall outcomes are not usually helpful. You want to be very specific and if you have friends/family in the medical field a little online research can help you understand the basic outcomes for BMT. They can also look at the CIBMTR website (below).If a BMT is indeed indicated, at the institution you are looking at how many have been performed and what have their outcomes been? Remember that for an allogeneic (donor) BMT complications can arise upto one year from transplant, and deaths in the first 100 days are now rare. So you are interested in knowing about all complications including how often GVHD occurs (where white cells from the donor attack the body, I am greatly oversimplifying) as well as infections etc, and how much more this will cost you to treat if it occurs?Is the hospital a member of CIBMTR (Centre for International Blood and Marrow Transplant Research) https://www.cibmtr.org/Pages/ind... recognized worldwide? CIBMTR also has some basic outcomes data for BMT procedures for anyone with a medical background.Remember that many patients and families are stressed and vulnerable and driven by a desire to do something, which makes it extremely hard to make decisions about this procedure. However I am cautiously optimistic that over the next 5–10 years there will be greater transparency in BMT in India which will ameliorate this issue.
Can Bone Marrow transplant ensure a blood Rh factor change from -ve to +ve?
Yes, your blood type can change after a stem cell transplant (that is the medically correct term for a bone marrow transplant) if your donor is a different type... the dna of your blood will also change to the dna of your donor. However, you dont want to go through all that just to change your blood type, I promise, and I am fairly certain you wont find a doc willing to do it for that purpose. You receive high dose chemo and radiation, are in the hospital for atleast 6 weeks straight, and then in daily outpatient clinice for atleast 6 weeks. Even if you did find a doc that would do it, no insurance would pay for doing this without a reason.... well, thats a gonna cost a couple million dollars.... literally... The blood bank services on the stem cells alone is phenomanal. And a year later, I am still medically unable to work, experiencing graft v host disease, and my monthly medicines cost about 2000$. EDIT: YES YES YES You need to look into trials. There are trials in the US that are or atleast were studying doing a stem cell transplant with other organ transplants when the organ and stem cells come from the same donor. This is partly for the reason you say, to make finding a donor easier, and will also give the patient a chance to come off all the immunosuppression meds!! Please look up trials on this!!!!
What don’t they tell you about chemotherapy?
They didn’t tell me that after 4 treatments of EC I would lose my major cephalic veins ( 1:1000 occurrence which is quite a risk in my eyes ) and they will never come back though the nurses insisted that I should wait. I did until more than a year of wearing my port-a-cath post treatment as they could not draw blood from the dead veins, I visited a vein specialist who told me to give up, they were gone forever.The spoke of a fatigue which is completely the wrong way of describing how you feel post EC chemotherapy session. As your red blood cells are decimated, you cannot really control your movements in the sense that your body does not send oxygen to all the parts of your body. I can imagine it is more like climbing Mount Everest than “fatigue”. You want to move but, your body cannot, it goes very slow motion.They did not tell me that having Taxol would cause so much pain, a bit like being hit with a sledge hammer and they send me home with a light painkiller for aches and pains for arthritis, completely wrong medication as Taxol attacks your nerve endings. The upside about Taxol, the smaller doses didn’t tire me any as I thought it would.They didn’t tell me ( or others ) that icing my feet and hands could help ward off nail damage ( onychopathy ) and most importantly, prolonged numbness of the extremities ( neuropathy ). Had to look it up myself.They did not tell me that chemotherapy could shorten my lifespan by 10 years. But so would cancer and most likely not by only 10 years.Would I do it again? 100% though would obviously take the necessary precautions against the side effects.You tend to hang on to every little percentage that will give you a bit more of a chance of survival. You add up the scans, the bone marrow biopsy ( a good way to check if there are any cancer circulating cells in your bone marrow though, nothing is 100% bulletproof ), the first surgery, the clearing the margins surgery, the chemotherapy, the second chemotherapy, the radiotherapy, the hormone therapy and hope that all those bits you suffered through, will be worth it.Five years later I am still alive though osteoporotic and heavily menopausal, my ability to remember new things has diminished considerably due to the EC chemo and the 100% menopause caused by the hormone therapy ( AIs, I take Letrozole ) and I am very thankful for it.Best wishes to all.