High Total Protein in Blood?
Your total protein is significantly elevated (not extremely, just mean it does not need to be blown off), and is likely due to something. One possibility is lab error, and the first thing may be to just repeat it. Myeloma is one explanation, and yes it is associated with bone pain, but... given you are not anemic (CBC is normal), unlikely myeloma at play here as if it is bad enough to give you bone pains diffusely, you would likely (but not 100%) have blood count abnormalities. Inflammation of any sort can cause similar findings, though usually a sed rate would be elevated in this situation (and yours really is not elevated much). So, while I think your doc is probably right about this, still it is prudent to get a serum protein electrophoresis (SPEP) as a next step- it will sort out if any abnormal proteins in the blood, and can sometimes tell if it is due to inflammatory (normal) proteins. BLessings
Elevated IGA from Celiac Disease Test. I do not have Celiac Disease…?
Hello Everyone, I have a curious question. What essentially is Elevated IGA? I have look all around google and there is not much information on it. Let me tell you my story… I went to an Endocrinologist to check on my testosterone because I am 33. I told him I was feeling okay maybe not the best so he did complete blood work on me. I did tell him that my Father was recently diagnosed with Celiac Disease so he went ahead and ran that as well. Long story short … the endocrinologist said that everything was perfect on me except that my IGA was elevated. His nurse at first gave me a call and said that this is probably no big deal and he just wants me to see a specialist. I was not understanding her so she just had the Doctor call me. He said that he had no idea what this mean and that “I would just not ignore it” kind of hinting that this could be a big deal.
Rehumatology test questions can you tell me what all of this means?
It all looks normal to me. You only had two tests above normal range, but that doesn't always mean anything.
What does it mean if you test borderline for rheumatoid arthritis?
Now, I may be wrong (in which case I apologize, of course), but my assumption is that you are actually asking what it means if your blood tests show a “Borderline Level of Rheumatoid FACTOR (not Rheumatoid Arthritis).” I'm assuming this because here is no such condition as “Borderline RA,” and it is generally the Rheumatoid Factor (RF) Blood Test that is the source of this concern/confusion.If I'm right and it is the “borderline RF” finding that is being asked about, then the answer is: not much.Loads and loads of people produce the RF antibody and have detectable levels of it. In most, there is never any disease diagnosed (though the higher the level, the more likely a condition will eventually be diagnosed).It's the sort of test that gets run when people are having either subtle confusing symptoms that might be one of many things (and so is sent looking for clues that point in one direction or another), OR in people who have symptoms at are very suggestive of RA (the disease), in which case, the presence of RF, as well as the level, has much more to do with prognosis and “typing” (how aggressive and what “flavor” of RA it is likely to be) than wi the diagnosis itself.Traditionally, there are two basic categories of Rheumatoid Arthritis (the disease - leaving aside juvenile vs adult-onset): “Sero-Negative” RA and “Sero-Positive” RA. The Postive and Negative refer to whether RF is found in the blood stream, BUT seriously-negativity does not in any way imply that a patient doesn't have RA. Somewhere in the range of 20–30% of patients with “full-blown” RA never test positive for RF in their blood (“serum” - hence “sero-”).Summary: the simple presence of the anti-body, RF (especially in lower ranges), does not in any way diagnose RA. It's the symptoms that are the foundation of the diagnosis. RF may or may not help with the diagnosis or the treatment (if the diagnosis is made), but it is not meaningful in the absence of the symptoms associated with RA. Of note, while the presence of RF at low levels is common and frequently indicates nothing significant, it may also be assorted with conditions other than RA.
High IgA and High IgE Levels.....What does it mean?
Without knowing additional bloodwork, the elevated IgA and IgE levels and symptoms you've mentioned could be caused by a variety of factors. The following link gives some basic information about possible causes of elevated levels. One common culprit is allergies. Autoimmune and parasitic issues could also be suspected. Also, take a look at "Hyper IgE Syndrome" on that link. http://www.greatplainslaboratory.com/hom... Typically, when abnormal antibody results come back a hematologist is then involved in the case. Have you been referred to one yet? If not, it sounds like it's time for one to get involved. From there, given your symptoms and antibody levels, you'll likely be referred to an allergist as well. Good luck, and take care!
What happens if the ANA results come back positive?
I mean....what will be the next step that we will take? Will they try to rule out other autoimmune disorders first or just immediately diagnose me with Lupus? What would be the first step in treating Lupus? Seriously, why do people have to be so f***ing ridiculous when they answer questions...if you don't have a real answer, then don't say anything. (Referring to Natasha)
What is the meaning of "biological reference interval"?
Biological reference interval (also called "decision values", or "reference range") a range of a value to decide whether a result of a certain examination is positive or negative to make clinical decision, so it is the responsibility of the laboratory to provide the correct biological reference intervals of all the examinations performed. These values must be representative for the population served by the laboratory and where necessary take into account factors such as age, sex or HIV-status.Note that for some examinations the biological reference intervals may vary per population and may be different for different populations of human beings around the world. So the range is usually decided by collecting data from the "normal" population, then put it in a frequency table and calculate its standard deviation. The result of the data should create a "bell curve chart" as shown in the image below, and we take the value of 95% of the population, which in turn could be defined as an interval of standard desviations between +1.96 and -1.96, rounding up to ±2.
ANA POSITIVE 1:80 and bordering RNP?
Hello, Six months ago, because of a hand rash, I made an ANA test which was 1:80 positive (FANA methode), and the anti-rnp was bordering 1:0, but the U1-rnp was negative. The other results of a complete ANA test were also negative. (CCP, IgG-abs, ds-DNA-ab, chromatine abs, SS-A/Ro(60kD), La/SS-B, Sm (B'B/D), U1-RNP/SM, Scl-70, Jo-1/Histidyl-tRNA-Synthet., Ribosomal P-protein abs, c-ANCA, p-ANCA, Cardiolipin-Ig-(G/M/A), B2-glycoprot.-1-ab, Lupus-anticoagulant, MAK/TPO-abs - all negative). I made a check up now and the results for ANA remain the same (1:80), the anti-rnp is little over border line 1.1 (border line is 1.0) and U1-rnp is again negative. I do not know what could this mean? I have never taken drugs that induce positive ANA. The doctor tells me the results are overlapping results, but I am very concerned about the following: - I don't feal any illness, but I am conserned if this could mean a begining of an autoimmune disease? - I am not sure if it's not dangerous for me to be pregnant. Could the pregnancy mean progress to the eventual ANA test result? - Could the already existing ANA test result in anyway damage the eventual baby? (I am 40, and it would be my first pregnancy) - In the last couple of weeks I feel very short and very tolerable pain in my palms and in my hand up to the elbows, but not in the elbows, could it be a sign of any autoimmune disease? Thanks very much indeed in advance to who ever answers me.
Cancer or side effect of RA?
I was wondering from my blood test what lymphocytes. Absolute 6.45 wbc 15.44 platelet 450 atypical lymphocyte 3.6. Pathology said lymphocytosis recommend flow cytometry thrombocytosis w I do have fibromyalgia and rheumatoid arthritis sed rate 23 C-reactive protein 1.9. Rheumatoid factor was 20 ccp igG antibody was 300.0 and my RA latex tuebid 70.1 My question is I have had blood issues since 2010 and I went to a hematologists then but said nothing was wrong may have been a cold or something should I fine a new hematologists because when I went I complain of pain then now in 2014 its like oh u have this and that?