What is the difference between the leading strand and the lagging strand in DNA replication?
A. The leading strand is synthesized in the 3′→5′ direction in a discontinuous fashion, while the lagging strand is synthesized in the 5′→3′ direction in a continuous fashion. B. The leading strand requires an RNA primer, whereas the lagging strand does not. C. The leading strand is synthesized continuously in the 5′→3′ direction, while the lagging strand is synthesized discontinuously in the 5′→3′ direction. D. There are different DNA polymerases involved in elongation of the leading strand and the lagging strand.
The leading and the lagging strands differ in that?
The leading and the lagging strands differ in that: a. the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction. b. the leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end. c. the lagging strand is synthesized continuously, whereas the leading strand is synthesized in short fragments that are ultimately stitched together. d. the leading strand is synthesized at twice the rate of the lagging strand.
Why is DNA replication slower in the laggin strand?
Because it is synthesised discontinuously in short lengths (Okazaki Fragments) and these have to be joined together by DNA ligase.
Lagging vs. leading strand?
*DNA REPLICATION* The Leading Strand - continuous, no complications Since DNA replication moves along the parent strand in the 5' to 3' direction, replication can occur very easily on the leading strand. RNA primase adds the first nucleotide to the newly forming chain, the DNA polymerase simply sits near the replication fork, moving as the fork does, adding nucleotides one after the other in continuous replication fashion.. The Lagging Strand - discontinuous The lagging strand replicates in small segments, called Okazaki fragments. These fragments are then stitched together by DNA ligase, creating a continuous strand. This type of replication is called discontinuous Leading and Lagging strand are terms having to do with DNA replication., where double stranded DNA makes one copy of itself. You start with one DNA and end up with two. An RNA PRIMER is used. *DNA CODES FOR PROTEINS* When we refer to a single stranded RNA we usually are talking about messenger RNA in Protein Synthesis which is a different process. DNA replicates itself and it also provides the code for proteins. In protein synthesis, DNA transcription and translation take place. During transcription, the DNA serves as a template for complementary base-pairing and RNA polymerase catalyzes the formation of a mRNA . The resulting mRNA is a single-stranded copy of the gene, which next must be translated into a protein molecule. Messenger RNA is needed because it can leave the nucleus (DNA does not leave) and go out in the cytoplasm to the ribosome. That is where the mRNA is transcribed into a protein by linking the amino acids together. http://www.accessexcellence.org/RC/VL/GG... - there is a diagram that puts ALL this together