What are the differences between mixtard insulin cartridges that are 50×50 and 30×70?
Mixtard 30/70 is the suspension of REGULAR HUMAN INSULIN 30% and NPH 70%Mixtard 50/50 is the suspension of REGULAR HUMAN INSULIN 50% and NPH 50%If the post meal glucose excursions are less then mixtard 30/70 would be preferred and if the postmeal glucose excursions are higher the mixtard 50/50 would be an better optionPls consult an endocrinologist/diabetologist for more information
When does Lantus (Solostar) start working after injection?
As you know, Lantus is a slow release acting insulin specifically designed for a 24 hour period., so it will act slowly but steadily, if your looking for immediate results then you should be on a fast acting insulin taken just before meals, depending on the amount of carbs. your eating. Lantus and other slow releasing forms of insulin should betaken by diabetics who have A1c's a bit higher than the recommended value....approx.6.5%, if your A1c's are above 7% than a faster acting form of insulin is required but you need to discuss this with your physician.
What's the difference between insulin nph and 70/30?
NPH(Neutralized Protamine Hagedorm) aka Protamine Insulin refers to an long acting preparation of Insulin. It has a moderately long duration of action and slower onset as compared to regular insulin.HM 30/70 is a mixture of Regular Insulin with Isophane Insulin in a 30:70 ratio.It is used a simpler alternative for administering the two different forms of insulin to the patient. The point is that goal of any regimen used for insulin based treatment is to replicate the natural curve of insulin concentration seen in the body, Ideally that means giving one very long acting preparation such as Insulin Glargine or Detemir or Degludec at night to meet the basal demands and then following it up with a very short acting preparation such as Insulin Lispro/Aspart/Glulisine just before EVERY meal. This would mean a myriad of inconvenient injections. This regimen is used mainly in Type 1 DM where insulin is necessary for survival. For Type 2 DM, we use HM 30/70 for convenience since it contains a moderately long acting and one intermediate acting insulin so, it is sort of a midway between the two extremes.Regular insulin in this preparation takes care of immediate post prandial hyperglycemia and Isophane Insulin takes care of reactionary hyperglycemia occuring after few hours of meal.
Is mixtard 30 considered as fast or slow insulin acting?
Mixtard 30/70 is Suspension for Injection, is a combination of two insulin preparations: Insulin Isophane / NPH(70%) and regular human insulin / soluble insulin(30%). Insulin Isophane / NPH has a prolonged duration of action while regular human insulin / soluble insulin has a fast onset of action. Together, they ensure rapid and consistent sugar control by facilitating reuptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.